Dietary grape powder effectively boosts cytokine production

A study published in the journal Nutrition Research reported that dietary powder made from grapes promotes cytokine production. In the study, researchers from the University of California, Davis used dietary recall data to determine if dietary patterns or the grape powder was the cause of increased cytokine production.

• In a randomized, double-blind crossover study, the scientists reported that the ingestion of dietary grape powder by obese volunteers increased the production of the proinflammatory cytokines interleukin 1 beta (IL-1B) and interleukin-6 (IL-6) by peripheral blood monocytes after stimulation with bacterial lipopolysaccharide.
• The research team speculated that the dietary grape powder increased the production of cytokines by stimulated monocytes.
• To test their hypothesis, the researchers used 24-hour dietary recall data to find out if differences in dietary patterns influenced increased cytokine production in the participants.
• They observed no differences in total energy, protein, carbohydrates, or fat intake in the diets between the grape powder and placebo intervention periods.
• Path analysis showed that the increased cytokine production by lipopolysaccharide-stimulated monocytes in obese participants was due to their intake of dietary grape powder, not the differences in food intake.

The researchers concluded that the consumption of dietary grape powder can promote cytokine production, particularly in obese individuals.

Learn more about other findings on food cures and the health benefits of dietary supplements at Scientific.news.

Journal Reference: 

Zunino SJ, Keim NL, Kelley DS, Bonnel EL, Souza EC, Peerson JM. INCREASED CYTOKINE PRODUCTION BY MONOCYTES FROM HUMAN SUBJECTS WHO CONSUMED GRAPE POWDER WAS NOT MEDIATED BY DIFFERENCES IN DIETARY INTAKE PATTERNS. Nutrition Research. April 2017;40:32–39. DOI: 10.1016/j.nutres.2017.03.001