Probiotics can help eliminate cadmium toxicity

Research has shown that probiotics can help eliminate cadmium in the body by binding to their bacterial cell wall and excreting through feces. The study, published in the Journal of Medicinal Food, examined the protective effects of probiotic supplementation against cadmium-induced toxicity in mice.

• Probiotics have the capacity to bind different targets and eliminate them through feces, and researchers at the University of Belgrade in Belgrade, Serbia and the University of Al Jabal Al Gharbi in Gharian, Libya hypothesized that one of these targets could be cadmium.
• Cadmium is a widespread environmental toxin that causes various disturbances in biological systems.
• For the five-week study, the researchers divided the mice into four groups: controls, probiotics treated, cadmium treated, and probiotic and cadmium-treated.
• They measured the cadmium concentration in the blood, liver, kidney, and feces, as well as the blood alanine aminotransferase (ALT) and aspartate aminotransferase (AST) as biomarkers of the liver function.
• They also assessed histomorphological changes in the liver and kidney.
• The results revealed that probiotics combined with cadmium increased cadmium’s concentration in feces.
• Therefore, cadmium levels in the blood, liver, kidney, blood ALT, and AST activities were lessened in mice treated with probiotics.
• In addition, probiotics consumed with cadmium weakened histomorphological changes in the liver and kidney caused by cadmium.
• The increase in lactobacilli number in feces of mice treated with probiotics correlates with the increase of cadmium concentration in their feces and the decline of cadmium concentration in their blood.

The researchers concluded that supplementation of probiotics can help eliminate cadmium in the body by binding to them and excreting them through feces.

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Journal Reference:

Djurasevic S, Jama A, Jasnic N, Vujovic P, Jovanovic M, Mitic-Culafic D, Knezevic-Vukcevic J, Cakic-Milosevic M, Ilijevic K, Djordjevic J. THE PROTECTIVE EFFECTS OF PROBIOTIC BACTERIA ON CADMIUM TOXICITY IN RATS. Journal of Medicinal Food. 1 February 2017; 20(2). DOI: 10.1089/jmf.2016.0090